Literature DB >> 12434129

[Platelet rich plasma (PRP): potentialities and techniques of extraction].

L Pacifici1, F Casella, C Maggiore.   

Abstract

This paper describes the various techniques of platelet-rich plasma (PRP) extraction codified in recent years and their use potential is evaluated. PRP is one of the techniques with which at the moment it is attempted to modulate and facilitate the cure of a wound. The use of PRP is based on the theoretical premise that by concentrating platelets the effects of the growth factors (PDGF, TGF-beta, IGF-I and -II) so released will be increased. Marx's original technique is described above all. This prescribes the sampling of a unit of blood (450-500 ml) and the use of a cell separator. We then analysed the technique of Marx and Hannon in which the quantity of blood sampled is reduced to 150 ml, and the two simplified techniques of the Sacchi and Bellanda group. Finally, a new PRP extraction technique is described. We conclude that platelet gel allows access to autologous growth factors which by definition are neither toxic nor immunogenic and are capable of accelerating the normal processes of bone regeneration. PRP can thus be considered a useful instrument for increasing the quality and final quantity of regenerated bone in oral and maxillo-facial surgery operations.

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Year:  2002        PMID: 12434129

Source DB:  PubMed          Journal:  Minerva Stomatol        ISSN: 0026-4970


  5 in total

1.  The effect of combination therapy on critical-size bone defects using non-activated platelet-rich plasma and adipose-derived stem cells.

Authors:  Woonhyeok Jeong; Young Seok Kim; Tai Suk Roh; Eun Hye Kang; Bok Ki Jung; In Sik Yun
Journal:  Childs Nerv Syst       Date:  2019-03-16       Impact factor: 1.475

2.  Combination of Controlled Release Platelet-Rich Plasma Alginate Beads and Bone Morphogenetic Protein-2 Genetically Modified Mesenchymal Stem Cells for Bone Regeneration.

Authors:  Gabriela Fernandes; Changdong Wang; Xue Yuan; Zunpeng Liu; Rosemary Dziak; Shuying Yang
Journal:  J Periodontol       Date:  2016-01-08       Impact factor: 6.993

3.  Platelet gel: applications in dental regenerative surgery.

Authors:  Franco Forni; Massimo Marzagalli; Patrizia Tesei; Alessandra Grassi
Journal:  Blood Transfus       Date:  2012-07-04       Impact factor: 3.443

Review 4.  Application of platelet-rich plasma with stem cells in bone and periodontal tissue engineering.

Authors:  Gabriela Fernandes; Shuying Yang
Journal:  Bone Res       Date:  2016-12-13       Impact factor: 13.567

5.  Platelet Rich Fibrin (P.R.F.) in reconstructive surgery of atrophied maxillary bones: clinical and histological evaluations.

Authors:  Marco Tatullo; Massimo Marrelli; Michele Cassetta; Andrea Pacifici; Luigi Vito Stefanelli; Salvatore Scacco; Gianna Dipalma; Luciano Pacifici; Francesco Inchingolo
Journal:  Int J Med Sci       Date:  2012-11-07       Impact factor: 3.738

  5 in total

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