Literature DB >> 12434126

[Early diagnosis of progressive systemic sclerosis: the role of oro-facial phenomena].

G A Scardina1, M Mazzullo, P Messina.   

Abstract

BACKGROUND: The study considers the oro-facial manifestations occurring in a group of patients suffering from progressive systemic sclerosis, evaluating their predictive role and monitoring the systemic disease.
METHODS: 34 patients with systemic sclerosis were examining: 30 women, 4 men, at the Department of Dental Sciences, Palermo University, from July 1998 to March 2001. All patients were positive for the diagnostic criteria of scleroderma.1 For each patient we considered: observation of any changes in soft tissues of the oral cavity; evaluation of possible xerostomia; evaluation of any fungal infections; presence of prosthetic sores in patients wearing dentures; DMFS evaluation; evaluation of periodontal health; evaluation of bone resorption.
RESULTS: One of the most interesting results was that: in 4 patients, medical history contained past trigeminal sensory neuropathy characterised by the slow and gradual numbness of the face muscles, which developed into pain and paresthesia, weakening or disappearance of the sense of taste and in one case loss of sensitivity at the oro-pharynx (this progression of symptoms preceded by three years the onset of systemic manifestations, and consequently diagnosis); 14 patients as first sign of the disease had a "hardening" of the skin of the face with consequent microstomia with marked difficulty in speaking.
CONCLUSIONS: The most significant result emerging from this study was the predictive role of progressive systemic sclerosis, that can be played by some oro-facial manifestations; an important element which has recently changed the life expectation for scleroderma patients is the possibility of diagnosing the disease in an early phase and thus bringing to bear all the therapeutic measures necessary to hinder development of the disease and its consequences.

Entities:  

Mesh:

Year:  2002        PMID: 12434126

Source DB:  PubMed          Journal:  Minerva Stomatol        ISSN: 0026-4970


  7 in total

1.  Oropharyngolaryngeal disorders in scleroderma: development and validation of the SLS scale.

Authors:  Chiara Vitali; Elisa Borghi; Arianna Napoletano; Francesca Polini; Monica Caronni; Paola Ammenti; Davide Cattaneo
Journal:  Dysphagia       Date:  2009-08-26       Impact factor: 3.438

2.  Instrumented Assessment of Oral Motor Function in Healthy Subjects and People with Systemic Sclerosis.

Authors:  Chiara Vitali; Cinzia Baldanzi; Francesca Polini; Angelo Montesano; Paola Ammenti; Davide Cattaneo
Journal:  Dysphagia       Date:  2015-02-17       Impact factor: 3.438

3.  Endothelin-1, α-Klotho, 25(OH) Vit D levels and severity of disease in scleroderma patients.

Authors:  Mehrzad Hajialilo; Parisa Noorabadi; Sepideh Tahsini Tekantapeh; Aida Malek Mahdavi
Journal:  Rheumatol Int       Date:  2017-08-22       Impact factor: 2.631

Review 4.  Orofacial consequences of systemic sclerosis: A systematic review.

Authors:  Rawen Smirani; Nicolas Poursac; Adrien Naveau; Thierry Schaeverbeke; Raphaël Devillard; Marie-Elise Truchetet
Journal:  J Scleroderma Relat Disord       Date:  2018-04-04

5.  Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies.

Authors:  Suhan Zhang; Junfei Zhu; Yanshan Zhu; Xiaochao Zhang; Ruifang Wu; Siying Li; Yuwen Su
Journal:  BMC Oral Health       Date:  2021-05-10       Impact factor: 2.757

6.  Endothelin-1 in systemic sclerosis.

Authors:  Mehrdad Aghaei; Farhad Gharibdost; Habib Zayeni; Maryam Akhlaghi; Sima Sedighi; Abduo Rahman Rostamian; Naser Aghdami; Mahdieh Shojaa
Journal:  Indian Dermatol Online J       Date:  2012-01

7.  Oral manifestations of Systemic Sclerosis and Correlation with anti-Topoisomerase I Antibodies (SCL-70).

Authors:  Ismet H Bajraktari; Avni Kryeziu; Fadil Sherifi; Halit Bajraktari; Ali Lahu; Genc Bajraktari
Journal:  Med Arch       Date:  2015-06-10
  7 in total

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