| Literature DB >> 12434114 |
Abstract
The neurotrophins NGF, BDNF, NT-3, and NT-4/5 are well known for their neuron survival-promoting functions. This review focuses upon a less-investigated function of this gene family, namely that of controlling the growth of axons in vivo. Recent evidence is discussed that reveals a definitive requirement for neurotrophin signaling in the elongation of peripheral nerves during embryonic development.Entities:
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Year: 2002 PMID: 12434114
Source DB: PubMed Journal: Panminerva Med ISSN: 0031-0808 Impact factor: 5.197