Jian-Min Liu1, Li Ma, Wei-Ping He. 1. Department of Otorhinolaryngology, Shenzhen Hospital of Guangdong General Command of Border Defense of Armed Police, China 518029.
Abstract
OBJECTIVE: To evaluate the therapeutic effect of puerarin in the treatment against sudden deafness. METHODS:Seventy-two patients with sudden deafness were randomly assigned into therapeutic group (n= 40) who received intravenous infusion of puerarin injection and the control group (n=32) who were given intravenous infusion of anisodamine. The therapeutic effects of the two treatments were observed and compared. RESULTS: The total efficacy rates against sudden deafness and tinnitus in the therapeutic group were 89.68 % and 84.37 % respectively, but only 62.5 % and 56.52 % respectively in the control group, showing significant difference (P<0.05). CONCLUSION:Puerarin is effective in dilating the blood vessels and promoting microcirculation of the inner ear, with significant therapeutic effect in the treatment of sudden deafness.
RCT Entities:
OBJECTIVE: To evaluate the therapeutic effect of puerarin in the treatment against sudden deafness. METHODS: Seventy-two patients with sudden deafness were randomly assigned into therapeutic group (n= 40) who received intravenous infusion of puerarin injection and the control group (n=32) who were given intravenous infusion of anisodamine. The therapeutic effects of the two treatments were observed and compared. RESULTS: The total efficacy rates against sudden deafness and tinnitus in the therapeutic group were 89.68 % and 84.37 % respectively, but only 62.5 % and 56.52 % respectively in the control group, showing significant difference (P<0.05). CONCLUSION:Puerarin is effective in dilating the blood vessels and promoting microcirculation of the inner ear, with significant therapeutic effect in the treatment of sudden deafness.