Literature DB >> 12432405

The language of genes.

David B Searls1.   

Abstract

Linguistic metaphors have been woven into the fabric of molecular biology since its inception. The determination of the human genome sequence has brought these metaphors to the forefront of the popular imagination, with the natural extension of the notion of DNA as language to that of the genome as the 'book of life'. But do these analogies go deeper and, if so, can the methods developed for analysing languages be applied to molecular biology? In fact, many techniques used in bioinformatics, even if developed independently, may be seen to be grounded in linguistics. Further interweaving of these fields will be instrumental in extending our understanding of the language of life.

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Year:  2002        PMID: 12432405     DOI: 10.1038/nature01255

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  49 in total

1.  The phylotypic stage as a boundary of modular memory: non mechanistic perspective.

Authors:  Jana Svorcová
Journal:  Theory Biosci       Date:  2012-02-10       Impact factor: 1.919

Review 2.  Annotating non-coding regions of the genome.

Authors:  Roger P Alexander; Gang Fang; Joel Rozowsky; Michael Snyder; Mark B Gerstein
Journal:  Nat Rev Genet       Date:  2010-07-13       Impact factor: 53.242

3.  Self-engineering capabilities of bacteria.

Authors:  Eshel Ben-Jacob; Herbert Levine
Journal:  J R Soc Interface       Date:  2006-02-22       Impact factor: 4.118

4.  The evolution of genomes and language.

Authors:  Hong-Yu Zhang
Journal:  EMBO Rep       Date:  2006-08       Impact factor: 8.807

5.  Language evolution as a Darwinian process: computational studies.

Authors:  Pierre-Yves Oudeyer; Frédéric Kaplan
Journal:  Cogn Process       Date:  2007-03

Review 6.  Syntactic structures in languages and biology.

Authors:  David Horn
Journal:  Cogn Process       Date:  2007-10-19

7.  Deadly competition between sibling bacterial colonies.

Authors:  Avraham Be'er; H P Zhang; E-L Florin; Shelley M Payne; Eshel Ben-Jacob; Harry L Swinney
Journal:  Proc Natl Acad Sci U S A       Date:  2009-01-07       Impact factor: 11.205

Review 8.  Computational methods in noncoding RNA research.

Authors:  Ariane Machado-Lima; Hernando A del Portillo; Alan Mitchell Durham
Journal:  J Math Biol       Date:  2007-09-04       Impact factor: 2.259

9.  Sequence-structure relations of pseudoknot RNA.

Authors:  Fenix W D Huang; Linda Y M Li; Christian M Reidys
Journal:  BMC Bioinformatics       Date:  2009-01-30       Impact factor: 3.169

10.  Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences.

Authors:  Derek Gatherer
Journal:  Bioinform Biol Insights       Date:  2009-11-24
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