Literature DB >> 12430725

Excitatory amino acids.

Mark G Moloney1.   

Abstract

Recent developments in the understanding of the molecular function of memory and other CNS-mediated processes have arisen from the multidisciplinary interplay of excitatory amino acid synthesis and medicinal chemistry, X-ray crystallographic structural protein analysis, molecular biology, pharmacology and physiology. This review seeks to place recent synthetic developments of EAA analogues in the wider pharmacological setting, illustrating the need for and importance of these compounds.

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Year:  2002        PMID: 12430725     DOI: 10.1039/b103777n

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


  4 in total

1.  Improved synthesis and in vitro/in vivo activities of natural product-inspired, artificial glutamate analogs.

Authors:  Masato Oikawa; Minoru Ikoma; Makoto Sasaki; Martin B Gill; Geoffrey T Swanson; Keiko Shimamoto; Ryuichi Sakai
Journal:  Bioorg Med Chem       Date:  2010-04-21       Impact factor: 3.641

2.  Nickel-catalyzed cyclizations of enoates and chiral allenes: an approach to domoic acid.

Authors:  Ahmad S ElDouhaibi; Refaie M Kassab; Minsoo Song; John Montgomery
Journal:  Chemistry       Date:  2011-04-27       Impact factor: 5.236

Review 3.  Ligands for ionotropic glutamate receptors.

Authors:  Geoffrey T Swanson; Ryuichi Sakai
Journal:  Prog Mol Subcell Biol       Date:  2009

4.  Total syntheses of isodomoic acids G and H: an exercise in tetrasubstituted alkene synthesis.

Authors:  Yike Ni; Refaie M Kassab; Maxim V Chevliakov; John Montgomery
Journal:  J Am Chem Soc       Date:  2009-12-09       Impact factor: 15.419

  4 in total

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