Literature DB >> 1242888

[Lethal intoxication with leaves of the yew tree (Taxus baccata) (author's transl)].

T Schulte.   

Abstract

A case of a rare lethal intoxication with yew leaves (taxus baccata) is reported. The clinical signs were dizziness (onset 1 hr after yew leaves were ingested), nausea, diffuse abdominal pain, unconsciousness, weak breathing, tachycardia, brief ventricular flutter afterwards a slow pulse, and finally death by respiratory arrest and diastolic cardiac standstill. Particular attention was given to the ECG. It showed an atypical bundle branch block with a maximal QRS-duration of 0.24 sec. A striking resemblence to the ECG in the case of hyperkalemia is seen in that P-waves were absent. Therefore, the possibility is noted that an acute hyperkalemia could be partly responsible for the cardiotoxic effect of the leaf.

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Year:  1975        PMID: 1242888     DOI: 10.1007/bf00353316

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  5 in total

1.  [Pharmacological properties of taxins A and B].

Authors:  R BAUEREIS; W STEIERT
Journal:  Arzneimittelforschung       Date:  1959-01

2.  [A fatal case of poisoning with Taxus baccata. Experiments on demonstration of Taxus alkaloid in the cadaver organs].

Authors:  H CZERWEK; W FISCHER
Journal:  Arch Toxikol       Date:  1960

3.  [Amorphous taxine & crystalline taxine A; Taxus alkaloids. II].

Authors:  E GRAF; H BERTHOLDT
Journal:  Pharm Zentralhalle Dtschl       Date:  1957 Aug-Sep

4.  [Study on beta-dimethylamino-hydrozimt acid].

Authors:  E GRAF; H BOEDDEKER
Journal:  Arch Pharm Ber Dtsch Pharm Ges       Date:  1956-07

5.  [Fatal poisoning with Taxus baccata].

Authors:  D Frohne; O Pribilla
Journal:  Arch Toxikol       Date:  1965
  5 in total
  4 in total

1.  [Psychiatric aspects of plant poisonings].

Authors:  W Kawohl; J Eckert; G Gerber-Zupan; E Habermeyer
Journal:  Nervenarzt       Date:  2005-07       Impact factor: 1.214

2.  Cardiovascular toxicity associated with yew leaf ingestion.

Authors:  J von der Werth; J J Murphy
Journal:  Br Heart J       Date:  1994-07

Review 3.  Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention.

Authors:  V B Pai; M C Nahata
Journal:  Drug Saf       Date:  2000-04       Impact factor: 5.606

4.  Suicidal yew leave ingestion--phloroglucindimethylether (3,5-dimethoxyphenol) as a marker for poisoning from Taxus baccata.

Authors:  F Musshoff; B Jacob; C Fowinkel; T Daldrup
Journal:  Int J Legal Med       Date:  1993       Impact factor: 2.686

  4 in total

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