OBJECTIVE: The authors conducted a longitudinal, population-based survey of African Americans in Indianapolis, Indiana, and Yoruba in Ibadan, Nigeria, using the Community Screening Interview for Dementia to assess the predictive value of informant reports of changes in personality on incident dementia and Alzheimer disease. METHODS: In all, 3,021 subjects had informants' reports of changes in personality and dementia status (2,084 subjects residing in Ibadan and 937 subjects residing in Indianapolis). RESULTS: After adjusting for demographic, cognitive, and functional characteristics in two markedly different populations, socioeconomically and culturally, subjects with changes in personality had approximately twice the odds of having dementia as subjects with no change in personality. CONCLUSION: The finding that in two markedly different populations, personality change is a significant predictor of future dementia, independent of cognition and functional status, should make clinicians particularly sensitive to these reports when they occur in their elderly patients.
OBJECTIVE: The authors conducted a longitudinal, population-based survey of African Americans in Indianapolis, Indiana, and Yoruba in Ibadan, Nigeria, using the Community Screening Interview for Dementia to assess the predictive value of informant reports of changes in personality on incident dementia and Alzheimer disease. METHODS: In all, 3,021 subjects had informants' reports of changes in personality and dementia status (2,084 subjects residing in Ibadan and 937 subjects residing in Indianapolis). RESULTS: After adjusting for demographic, cognitive, and functional characteristics in two markedly different populations, socioeconomically and culturally, subjects with changes in personality had approximately twice the odds of having dementia as subjects with no change in personality. CONCLUSION: The finding that in two markedly different populations, personality change is a significant predictor of future dementia, independent of cognition and functional status, should make clinicians particularly sensitive to these reports when they occur in their elderly patients.
Authors: Marc Sollberger; John Neuhaus; Robin Ketelle; Christine M Stanley; Victoria Beckman; Matthew Growdon; Jung Jang; Bruce L Miller; Katherine P Rankin Journal: J Neurol Neurosurg Psychiatry Date: 2010-12-15 Impact factor: 10.154
Authors: Tomiko Yoneda; Jonathan Rush; Eileen K Graham; Anne Ingeborg Berg; Hannie Comijs; Mindy Katz; Richard B Lipton; Boo Johansson; Daniel K Mroczek; Andrea M Piccinin Journal: J Gerontol B Psychol Sci Soc Sci Date: 2020-01-14 Impact factor: 4.077
Authors: Antonio Terracciano; Yang An; Angelina R Sutin; Madhav Thambisetty; Susan M Resnick Journal: JAMA Psychiatry Date: 2017-12-01 Impact factor: 21.596
Authors: Richard J Caselli; Blake T Langlais; Amylou C Dueck; Bruce R Henslin; Travis A Johnson; Bryan K Woodruff; Charlene Hoffman-Snyder; Dona E C Locke Journal: J Am Geriatr Soc Date: 2018-01-17 Impact factor: 5.562