Literature DB >> 12427332

A statistical method for analyzing rating scale data: the BBB locomotor score.

Stephen W Scheff1, Donald A Saucier, Mary E Cain.   

Abstract

The Basso, Beattie and Bresnahan (BBB) locomotor rating scale is widely used to test behavioral consequences of spinal cord injury (SCI) to the rat. Sensitivity of this rating scale can differentiate hind limb locomotor skills over a wide range of injury severities. While the 21-point BBB scale is ordinal in nature, the present discussion recommends the use of parametric statistics to evaluate the locomotor results. Specifically, it defines appropriate statistical analysis of these data in order to facilitate interpretation of results between laboratories and to provide a common methodology for the correct interpretation of SCI behavioral data.

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Year:  2002        PMID: 12427332     DOI: 10.1089/08977150260338038

Source DB:  PubMed          Journal:  J Neurotrauma        ISSN: 0897-7151            Impact factor:   5.269


  43 in total

1.  Design and assessment of a potent sodium channel blocking derivative of mexiletine for minimizing experimental neuropathic pain in several rat models.

Authors:  Robert M Weston; Kamani R Subasinghe; Vasiliki Staikopoulos; Bevyn Jarrott
Journal:  Neurochem Res       Date:  2009-06-06       Impact factor: 3.996

2.  Non-invasive stimulation of the vibrissal pad improves recovery of whisking function after simultaneous lesion of the facial and infraorbital nerves in rats.

Authors:  H Bendella; S P Pavlov; M Grosheva; A Irintchev; S K Angelova; D Merkel; N Sinis; K Kaidoglou; E Skouras; S A Dunlop; Doychin N Angelov
Journal:  Exp Brain Res       Date:  2011-04-28       Impact factor: 1.972

3.  Acute molecular perturbation of inducible nitric oxide synthase with an antisense approach enhances neuronal preservation and functional recovery after contusive spinal cord injury.

Authors:  Dominic M Maggio; Katina Chatzipanteli; Neil Masters; Samik P Patel; W Dalton Dietrich; Damien D Pearse
Journal:  J Neurotrauma       Date:  2012-08-10       Impact factor: 5.269

4.  Spinal cord injury with unilateral versus bilateral primary hemorrhage--effects of glibenclamide.

Authors:  J Marc Simard; Phillip G Popovich; Orest Tsymbalyuk; Volodymyr Gerzanich
Journal:  Exp Neurol       Date:  2011-12-14       Impact factor: 5.330

5.  Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats.

Authors:  Hai-Hu Hao; Li Wang; Zhi-Jian Guo; Lang Bai; Rui-Ping Zhang; Wei-Bing Shuang; Yi-Jia Jia; Jie Wang; Xiao-Yu Li; Qiang Liu
Journal:  Neurosci Bull       Date:  2013-07-13       Impact factor: 5.203

6.  Protective effects of Batroxobin on spinal cord injury in rats.

Authors:  Hong Fan; Xia Liu; Hai-Bin Tang; Peng Xiao; Ya-Zhou Wang; Gong Ju
Journal:  Neurosci Bull       Date:  2013-07-13       Impact factor: 5.203

7.  Combined nonlinear metrics to evaluate spontaneous EEG recordings from chronic spinal cord injury in a rat model: a pilot study.

Authors:  Jiangbo Pu; Hanhui Xu; Yazhou Wang; Hongyan Cui; Yong Hu
Journal:  Cogn Neurodyn       Date:  2016-07-01       Impact factor: 5.082

8.  Trem1 mediates neuronal apoptosis via interaction with SYK after spinal cord ischemia-reperfusion injury.

Authors:  Wei Shi; Yanqing Sun; Juncheng Wang; Yifan Tang; Shengyuan Zhou; Zheng Xu; Bo Yuan; Xiangwu Geng; Xiongsheng Chen
Journal:  Am J Transl Res       Date:  2021-06-15       Impact factor: 4.060

9.  Robust axonal growth and a blunted macrophage response are associated with impaired functional recovery after spinal cord injury in the MRL/MpJ mouse.

Authors:  S K Kostyk; P G Popovich; B T Stokes; P Wei; L B Jakeman
Journal:  Neuroscience       Date:  2008-08-19       Impact factor: 3.590

10.  Analysis of the sensitivity and reproducibility of the Basso, Beattie, Bresnahan (BBB) scale in Wistar rats.

Authors:  Tarcisio Eloy Pessoa de Barros Filho; Alessandra Eira Iague Sleiman Molina
Journal:  Clinics (Sao Paulo)       Date:  2008-02       Impact factor: 2.365

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