Literature DB >> 12426771

Neonatal rat cardiomyocytes--a model for the study of morphological, biochemical and electrophysiological characteristics of the heart.

S Chlopcíková1, J Psotová, P Miketová.   

Abstract

The neonatal rat cardiomyocyte model enables heart researchers to study and understand the morphological, biochemical and electrophysiological characteristics of the heart. This model offers a broad spectrum of experiments, such as studies of contraction, ischaemia, hypoxia and the toxicity of various compounds. This review examines the methodology for the isolation and cultivation of primary neonatal rat cardiomyocyte cultures, considers possible problems and pitfalls, and presents an optimized protocol for cardiomyocyte preparation.

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Year:  2001        PMID： 12426771

Source DB:  PubMed          Journal:  Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub        ISSN： 1213-8118            Impact factor:   1.245


  36 in total

1.  Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

Authors:  Chang-Hoon Woo; Nhat-Tu Le; Tetsuro Shishido; Eugene Chang; Hakjoo Lee; Kyung-Sun Heo; Deanne M Mickelsen; Yan Lu; Carolyn McClain; Thomas Spangenberg; Chen Yan; Carlos A Molina; Jay Yang; Cam Patterson; Jun-ichi Abe
Journal:  FASEB J       Date:  2010-08-19       Impact factor: 5.191

2.  Reconstitution of the Frank-Starling mechanism in engineered heart tissues.

Authors:  Clara F Asnes; J Pablo Marquez; Elliot L Elson; Tetsuro Wakatsuki
Journal:  Biophys J       Date:  2006-06-16       Impact factor: 4.033

3.  An improved protocol for primary culture of cardiomyocyte from neonatal mice.

Authors:  P Sreejit; Suresh Kumar; Rama S Verma
Journal:  In Vitro Cell Dev Biol Anim       Date:  2008-02-23       Impact factor: 2.416

4.  Biomimetic microstructure morphology in electrospun fiber mats is critical for maintaining healthy cardiomyocyte phenotype.

Authors:  Rutwik Rath; Jung Bok Lee; Truc-Linh Tran; Sean F Lenihan; Cristi L Galindo; Yan Ru Su; Tarek Absi; Leon M Bellan; Douglas B Sawyer; Hak-Joon Sung
Journal:  Cell Mol Bioeng       Date:  2015-09-08       Impact factor: 2.321

5.  Novel fluorescence resonance energy transfer-based reporter reveals differential calcineurin activation in neonatal and adult cardiomyocytes.

Authors:  Hojjat Bazzazi; Lingjie Sang; Ivy E Dick; Rosy Joshi-Mukherjee; Wanjun Yang; David T Yue
Journal:  J Physiol       Date:  2015-07-22       Impact factor: 5.182

6.  Profiling of skeletal muscle Ankrd2 protein in human cardiac tissue and neonatal rat cardiomyocytes.

Authors:  Jovana Jasnic-Savovic; Aleksandra Nestorovic; Slobodan Savic; Sinisa Karasek; Nicola Vitulo; Giorgio Valle; Georgine Faulkner; Dragica Radojkovic; Snezana Kojic
Journal:  Histochem Cell Biol       Date:  2015-01-14       Impact factor: 4.304

7.  Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart disease.

Authors:  W J de Lange; L F Hegge; A C Grimes; C W Tong; T M Brost; R L Moss; J C Ralphe
Journal:  Circ Res       Date:  2011-05-12       Impact factor: 17.367

8.  Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts.

Authors:  Rajeshwary Ghosh; Sumanta K Goswami; Luis Felipe B B Feitoza; Bruce Hammock; Aldrin V Gomes
Journal:  Int J Cardiol       Date:  2016-08-13       Impact factor: 4.164

9.  Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.

Authors:  Eric C Lin; Katherine M Holzem; Blake D Anson; Brooke M Moungey; Sadguna Y Balijepalli; David J Tester; Michael J Ackerman; Brian P Delisle; Ravi C Balijepalli; Craig T January
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-04-02       Impact factor: 4.733

10.  Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure.

Authors:  Bo Ding; Jun-Ichi Abe; Heng Wei; Qunhua Huang; Richard A Walsh; Carlos A Molina; Allan Zhao; Junichi Sadoshima; Burns C Blaxall; Bradford C Berk; Chen Yan
Journal:  Circulation       Date:  2005-05-02       Impact factor: 29.690
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