| Literature DB >> 12424384 |
K Richard Ridderinkhof1, Yolande de Vlugt, Aldo Bramlage, Marcus Spaan, Martin Elton, Jan Snel, Guido P H Band.
Abstract
The anterior cingulate cortex (ACC) is a critical component of the human mediofrontal neural circuit that monitors ongoing processing in the cognitive system for signs of erroneous outcomes. Here, we show that the consumption of alcohol in moderate doses induces a significant deterioration of the ability to detect the activation of erroneous responses as reflected in the amplitude of brain electrical activity associated with the ACC. This impairment was accompanied by failures to instigate performance adjustments after these errors. These findings offer insights into how the effects of alcohol on mediofrontal brain function may result in compromised performance.Entities:
Mesh:
Substances:
Year: 2002 PMID: 12424384 DOI: 10.1126/science.1076929
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728