Literature DB >> 12423970

Synthesis of natural beta-D-(1-->3)-glucopyranosyl oligosaccharides.

Hongmei He1, Feng Yang, Yuguo Du.   

Abstract

beta-D-(1-->3)-Glucan core structure derivatives corresponding to schizophyllan, epiglucan and lentinan were synthesized efficiently. 4,6-O-Benzylidenated glucopyranosyl acceptors were found to be helpful in the attempted beta-D-(1-->3) bond formation. The epiglucan pentasaccharide showed a weak anti-tumor activity in preliminary mice tests.

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Year:  2002        PMID: 12423970     DOI: 10.1016/s0008-6215(02)00276-8

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  3 in total

1.  Facile synthesis of saponins containing 2,3-branched oligosaccharides by using partially protected glycosyl donors.

Authors:  Guofeng Gu; Yuguo Du; Robert J Linhardt
Journal:  J Org Chem       Date:  2004-08-06       Impact factor: 4.354

2.  Synthetic oligosaccharide stimulates and stabilizes angiogenesis: structure-function relationships and potential mechanisms.

Authors:  S A Mousa; X Feng; J Xie; Y Du; Y Hua; H He; L O'Connor; R J Linhardt
Journal:  J Cardiovasc Pharmacol       Date:  2006-08       Impact factor: 3.271

3.  Immunomodulatory activity of a novel, synthetic beta-glucan (β-glu6) in murine macrophages and human peripheral blood mononuclear cells.

Authors:  Xiaofei Li; Jing Wang; Wei Wang; Chunhong Liu; Shuhui Sun; Jianxin Gu; Xun Wang; Diana Boraschi; Yuxian Huang; Di Qu
Journal:  PLoS One       Date:  2013-11-06       Impact factor: 3.240

  3 in total

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