Literature DB >> 12423114

Solid-phase, Pd-catalyzed silicon-aryl carbon bond formation. Synthesis of sansalvamide A peptide.

Wenxin Gu1, Shouxin Liu S, Richard B Silverman.   

Abstract

A palladium-catalyzed silicon-aryl carbon bond formation on solid-phase is reported. A phenylalanine silane resin was prepared directly from protected iodo-substituted phenylalanine with butyl diethylsilane polystyrene in one step. A rapid and high-yield solid-phase synthesis of sansalvamide A peptide was achieved from the phenylalanine silane resin. [reaction: see text]

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Year:  2002        PMID： 12423114     DOI： 10.1021/ol0269392

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

1.  Design and synthesis of Hsp90 inhibitors: exploring the SAR of Sansalvamide A derivatives.

Authors:  Robert P Sellers; Leslie D Alexander; Victoria A Johnson; Chun-Chieh Lin; Jeremiah Savage; Ricardo Corral; Jason Moss; Tim S Slugocki; Erinprit K Singh; Melinda R Davis; Suchitra Ravula; Jamie E Spicer; Jenna L Oelrich; Andrea Thornquist; Chung-Mao Pan; Shelli R McAlpine
Journal:  Bioorg Med Chem       Date:  2010-07-22       Impact factor: 3.641

2.  Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification.

Authors:  Shengxi Chen; Nour Eddine Fahmi; Chandrabali Bhattacharya; Lin Wang; Yuguang Jin; Stephen J Benkovic; Sidney M Hecht
Journal:  Biochemistry       Date:  2013-11-11       Impact factor: 3.162

Review 3.  Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.

Authors:  Gaurav Garg; Anuj Khandelwal; Brian S J Blagg
Journal:  Adv Cancer Res       Date:  2016-02-10       Impact factor: 6.242

4.  Synthesis and biological evaluation of histone deacetylase inhibitors that are based on FR235222: a cyclic tetrapeptide scaffold.

Authors:  Erinprit K Singh; Suchitra Ravula; Chung-Mao Pan; Po-Shen Pan; Robert C Vasko; Stephanie A Lapera; Sujith V W Weerasinghe; Mary Kay H Pflum; Shelli R McAlpine
Journal:  Bioorg Med Chem Lett       Date:  2008-03-20       Impact factor: 2.823

5.  A comprehensive study of Sansalvamide A derivatives: The structure-activity relationships of 78 derivatives in two pancreatic cancer cell lines.

Authors:  Po-Shen Pan; Robert C Vasko; Stephanie A Lapera; Victoria A Johnson; Robert P Sellers; Chun-Chieh Lin; Chung-Mao Pan; Melinda R Davis; Veronica C Ardi; Shelli R McAlpine
Journal:  Bioorg Med Chem       Date:  2009-07-15       Impact factor: 3.641

Review 6.  The current status of natural products from marine fungi and their potential as anti-infective agents.

Authors:  Punyasloke Bhadury; Balsam T Mohammad; Phillip C Wright
Journal:  J Ind Microbiol Biotechnol       Date:  2006-01-21       Impact factor: 4.258

7.  A well-defined NHC-Ir(iii) catalyst for the silylation of aromatic C-H bonds: substrate survey and mechanistic insights.

Authors:  Laura Rubio-Pérez; Manuel Iglesias; Julen Munárriz; Victor Polo; Vincenzo Passarelli; Jesús J Pérez-Torrente; Luis A Oro
Journal:  Chem Sci       Date:  2017-04-05       Impact factor: 9.825

8.  Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts.

Authors:  Nicholas R Waterfield; Maria Sanchez-Contreras; Ioannis Eleftherianos; Andrea Dowling; Guowei Yang; Paul Wilkinson; Julian Parkhill; Nicholas Thomson; Stuart E Reynolds; Helge B Bode; Steven Dorus; Richard H Ffrench-Constant
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-06       Impact factor: 11.205

9.  Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids.

Authors:  Angélica de Fátima S Barreto; Otilie E Vercillo; Ludger A Wessjohann; Carlos Kleber Z Andrade
Journal:  Beilstein J Org Chem       Date:  2014-05-05       Impact factor: 2.883
  9 in total

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