Literature DB >> 12423097

Silicon tether-aided coupling metathesis: application to the synthesis of attenol A.

Pierre Van de Weghe1, Darina Aoun, Jean-Guy Boiteau, Jacques Eustache.   

Abstract

A new synthesis of attenol A is described. Key features of this work include a crucial silicon tether-aided coupling metathesis step and the use of iodoetherification as an efficient protection method for 1,5-ene-ols. [reaction: see text]

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12423097     DOI： 10.1021/ol0268438

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade.

Authors:  Mohammad Movassaghi; Grazia Piizzi; Dustin S Siegel; Giovanni Piersanti
Journal:  Tetrahedron Lett       Date:  2009-09-30       Impact factor: 2.415

2.  Phosphate-tether-mediated ring-closing metathesis for the preparation of complex 1,3-anti-diol-containing subunits.

Authors:  Rambabu Chegondi; Soma Maitra; Jana L Markley; Paul R Hanson
Journal:  Chemistry       Date:  2013-05-24       Impact factor: 5.236

3.  Enantioselective total synthesis of the potent antitumor agent (-)-mucocin using a temporary silicon-tethered ring-closing metathesis cross-coupling reaction.

Authors:  P Andrew Evans; Jian Cui; Santosh J Gharpure; Alexei Polosukhin; Hai-Ren Zhang
Journal:  J Am Chem Soc       Date:  2003-12-03       Impact factor: 15.419

4.  A reductive cyclization approach to attenol A.

Authors:  Thomas E La Cruz; Scott D Rychnovsky
Journal:  J Org Chem       Date:  2007-03-09       Impact factor: 4.354

Review 5.  Asymmetric synthesis of naturally occurring spiroketals.

Authors:  B Rama Raju; Anil K Saikia
Journal:  Molecules       Date:  2008-08-28       Impact factor: 4.411

6.  An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis.

Authors:  Christopher Cordier; Daniel Morton; Stuart Leach; Thomas Woodhall; Catherine O'Leary-Steele; Stuart Warriner; Adam Nelson
Journal:  Org Biomol Chem       Date:  2008-04-10       Impact factor: 3.876
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.