Literature DB >> 12423096

Molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks.

Geoffrey K Tranmer1, William Tam.   

Abstract

The molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks were investigated. A tandem N-O bond cleavage-retro aldol reaction of an isoxazoline ring fused in a bicyclic framework led to the cleavage of the bicyclic framework. These reactions provide a novel stereoselective synthesis of substituted cyclopentene rings, cyclopentane rings, and attached-ring systems. [reaction: see text]

Entities:  

Year:  2002        PMID： 12423096     DOI： 10.1021/ol026846k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Intramolecular Pd-catalyzed carboetherification and carboamination. Influence of catalyst structure on reaction mechanism and product stereochemistry.

Authors:  Josephine S Nakhla; Jeff W Kampf; John P Wolfe
Journal:  J Am Chem Soc       Date:  2006-03-08       Impact factor: 15.419

2.  1-(3-Hy-droxy-5,8-dimeth-oxy-4-methyl-1,2,3,4-tetra-hydro-1,4-ep-oxy-naphthalen-2-yl)ethan-1-one.

Authors:  Alan J Lough; Jaipal R Nagireddy; William Tam
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-04-12

3.  Ruthenium-Catalyzed [2 + 2] versus Homo Diels-Alder [2 + 2 + 2] Cycloadditions of Norbornadiene and Disubstituted Alkynes: A DFT Study.

Authors:  Austin Pounder; Leanne D Chen; William Tam
Journal:  ACS Omega       Date:  2020-12-18

4.  Access to β-Alkylated γ-Functionalized Ketones via Conjugate Additions to Arylideneisoxazol-5-ones and Mo(CO)6-Mediated Reductive Cascade Reactions.

Authors:  Antonio Macchia; Francesco F Summa; Guglielmo Monaco; Andreas Eitzinger; Armin R Ofial; Antonia Di Mola; Antonio Massa
Journal:  ACS Omega       Date:  2022-03-04

5.  N-O Cleavage reactions of heterobicycloalkene-fused 2-isoxazolines.

Authors:  Jaipal R Nagireddy; Geoffrey K Tranmer; Emily Carlson; William Tam
Journal:  Beilstein J Org Chem       Date:  2014-09-16       Impact factor: 2.883
  5 in total

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