Literature DB >> 12423085

Microwave-assisted solid-phase synthesis of peptoids.

Hernando J Olivos1, Prasanna G Alluri, M Muralidhar Reddy, Derek Salony, Thomas Kodadek.   

Abstract

Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods. [reaction: see text]

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Year:  2002        PMID: 12423085     DOI: 10.1021/ol0267578

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  43 in total

1.  Protein "fingerprinting" in complex mixtures with peptoid microarrays.

Authors:  M Muralidhar Reddy; Thomas Kodadek
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-25       Impact factor: 11.205

2.  Synthetic ligands discovered by in vitro selection.

Authors:  S Jarrett Wrenn; Rebecca M Weisinger; David R Halpin; Pehr B Harbury
Journal:  J Am Chem Soc       Date:  2007-10-06       Impact factor: 15.419

3.  Quantitative evaluation of the relative cell permeability of peptoids and peptides.

Authors:  Yong-Uk Kwon; Thomas Kodadek
Journal:  J Am Chem Soc       Date:  2007-02-14       Impact factor: 15.419

4.  Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein.

Authors:  Misook Oh; Ji Hoon Lee; Wei Wang; Hui Sun Lee; Woo Sirl Lee; Christopher Burlak; Wonpil Im; Quyen Q Hoang; Hyun-Suk Lim
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-14       Impact factor: 11.205

5.  Identification of the minimum pharmacophore of lipid-phosphatidylserine (PS) binding peptide-peptoid hybrid PPS1D1.

Authors:  Jaspal Singh; Satya Prakash Shukla; Tanvi J Desai; D Gomika Udugamasooriya
Journal:  Bioorg Med Chem       Date:  2016-07-21       Impact factor: 3.641

6.  Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9.

Authors:  Xiaodan Liu; Melissa Dix; Anna E Speers; Daniel A Bachovchin; Andrea M Zuhl; Benjamin F Cravatt; Thomas J Kodadek
Journal:  Chembiochem       Date:  2012-08-20       Impact factor: 3.164

7.  Effect of microwave radiation on enzymatic and chemical Peptide bond synthesis on solid phase.

Authors:  Alessandra Basso; Loris Sinigoi; Lucia Gardossi; Sabine Flitsch
Journal:  Int J Pept       Date:  2009-03-25

8.  Isolation of antagonists of antigen-specific autoimmune T cell proliferation.

Authors:  Anne R Gocke; D Gomika Udugamasooriya; Chase T Archer; Jiyong Lee; Thomas Kodadek
Journal:  Chem Biol       Date:  2009-11-25

9.  Selective toxin sequestrants for the treatment of bacterial infections.

Authors:  Levi S Simpson; Lyle Burdine; Amal K Dutta; Andrew P Feranchak; Thomas Kodadek
Journal:  J Am Chem Soc       Date:  2009-04-29       Impact factor: 15.419

10.  Sequence-Defined Oligomers from Hydroxyproline Building Blocks for Parallel Synthesis Applications.

Authors:  Rosemary L Kanasty; Arturo J Vegas; Luke M Ceo; Martin Maier; Klaus Charisse; Jayaprakash K Nair; Robert Langer; Daniel G Anderson
Journal:  Angew Chem Int Ed Engl       Date:  2016-07-01       Impact factor: 15.336

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