Platelet therapy.

Thrombocytopenia is a major cause of bleeding episodes at all ages. The pathophysiology, causes of thrombocytopenia and clinical presentation have been reviewed briefly. However the emphasis has been laid on various aspects of platelet support such as indications and amount of platelet support essential for management of bleeding episodes with the help of platelet concentrates, single donor platelets. Strategies for management of platelet transfusion refractoriness has also been included for effective management of bleeding episodes in these conditions.