| Literature DB >> 12419496 |
Seong Min Ra1, Hong Kim, Mi Hyeon Jang, Min Chul Shin, Taeck Hyun Lee, Baek Vin Lim, Chang Ju Kim, Ee Hwa Kim, Kyeong Mi Kim, Sung Soo Kim.
Abstract
The effects of treadmill exercise and swimming on cell proliferation in the dentate gyrus and the involvement of opioid receptors were investigated via 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry. Sprague-Dawley rats of the running groups were made to run on treadmill for 30 min each day, while those of the swimming groups were made to swim for 5 min each day over 3 consecutive days. In addition, intensity-dependency of the effects of running and swimming on cell proliferation was investigated. The present results demonstrate that both treadmill running and swimming increase the number of BrdU-labeled cells in the dentate gyrus and these increasing effects are more potent in light intensity and 5 min swimming groups. Treatment with naloxone increases cell proliferation in the dentate gyrus in all groups, although this increase is statistically insignificant.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12419496 DOI： 10.1016/s0304-3940(02)01031-5
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046