| Literature DB >> 12419240 |
Abstract
The histone tails on the nucleosome surface are subject to enzyme-catalyzed modifications that may, singly or in combination, form a code specifying patterns of gene expression. Recent papers provide insights into how a combinatorial code might be set and read. They show how modification of one residue can influence that of another, even when they are located on different histones, and how modifications at specific genomic locations might be perpetuated on newly assembled chromatin.Mesh:
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Year: 2002 PMID: 12419240 DOI: 10.1016/s0092-8674(02)01080-2
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582