| Literature DB >> 12418569 |
J M Shand1, A A C Heggie, A D Holmes, W Holmes.
Abstract
The purpose of this study was to investigate the incorporation of fresh frozen irradiated membranous allogeneic bone grafts into critical size calvarial defects in the rabbit. Fifteen rabbits had calvarial defects prepared. Twelve rabbits received allogeneic grafts and three received autogenous bone grafts. The rabbits were sacrificed at 9 and 12 months postoperatively, and the specimens were examined radiologically, histopathologically and with fluorescence microscopy. Neovascularization, bone marrow regeneration and new bone formation was evident throughout the grafts however revitalization of the entire graft was incomplete at 12 months. This study revealed that the FFI membranous grafts were well incorporated into rabbit calvarial defects.Entities:
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Year: 2002 PMID: 12418569 DOI: 10.1054/ijom.2002.0281
Source DB: PubMed Journal: Int J Oral Maxillofac Surg ISSN: 0901-5027 Impact factor: 2.789