Literature DB >> 12417297

Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10.

Lamei Cheng1, Kouichi Tachibana, Yan Zhang, Jian ming Guo, Kahori Kahori Tachibana, Akihiko Kameyama, Han Wang, Toru Hiruma, Hiroko Iwasaki, Akira Togayachi, Takashi Kudo, Hisashi Narimatsu.   

Abstract

A novel member of the human UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (pp-GalNAc-T) gene family was cloned as a homolog of human pp-GalNAc-T7, and designated pp-GalNAc-T10. pp-GalNAc-T10 transcript was found in the small intestine, stomach, pancreas, ovary, thyroid gland and spleen. In a polypeptide GalNAc-transfer assay, recombinant pp-GalNAc-T10 transferred GalNAc onto a panel of mucin-derived peptide substrates. Furthermore, pp-GalNAc-T10 demonstrated strong transferase activity with glycopeptide substrates.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12417297     DOI： 10.1016/s0014-5793(02)03399-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  27 in total

1.  Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis.

Authors:  Yun Kong; Hiren J Joshi; Katrine Ter-Borch Gram Schjoldager; Thomas Daugbjerg Madsen; Thomas A Gerken; Malene B Vester-Christensen; Hans H Wandall; Eric Paul Bennett; Steven B Levery; Sergey Y Vakhrushev; Henrik Clausen
Journal:  Glycobiology       Date:  2014-08-25       Impact factor: 4.313

2.  Construction of a library of human glycosyltransferases immobilized in the cell wall of Saccharomyces cerevisiae.

Authors:  Yoh-Ichi Shimma; Fumie Saito; Fumi Oosawa; Yoshifumi Jigami
Journal:  Appl Environ Microbiol       Date:  2006-08-25       Impact factor: 4.792

3.  Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases.

Authors:  Thomas A Gerken; Oliver Jamison; Cynthia L Perrine; Jeremy C Collette; Helen Moinova; Lakshmeswari Ravi; Sanford D Markowitz; Wei Shen; Himatkumar Patel; Lawrence A Tabak
Journal:  J Biol Chem       Date:  2011-02-24       Impact factor: 5.157

4.  Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study.

Authors:  Chuanhui Dong; David Della-Morte; Ashley Beecham; Liyong Wang; Digna Cabral; Susan H Blanton; Ralph L Sacco; Tatjana Rundek
Journal:  Atherosclerosis       Date:  2015-04-16       Impact factor: 5.162

Review 5.  Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

Authors:  Eric P Bennett; Ulla Mandel; Henrik Clausen; Thomas A Gerken; Timothy A Fritz; Lawrence A Tabak
Journal:  Glycobiology       Date:  2011-12-18       Impact factor: 4.313

6.  Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics.

Authors:  Yoshiki Narimatsu; Hiren J Joshi; Katrine T Schjoldager; John Hintze; Adnan Halim; Catharina Steentoft; Rebecca Nason; Ulla Mandel; Eric P Bennett; Henrik Clausen; Sergey Y Vakhrushev
Journal:  Mol Cell Proteomics       Date:  2019-04-30       Impact factor: 5.911

7.  Expression pattern of polypeptide N-acetylgalactosaminyltransferase-10 in gastric carcinoma.

Authors:  Yuan Gao; Zhenhua Liu; Jinghua Feng; Qizhe Sun; Bao Zhang; Wenling Zheng; Wenli Ma
Journal:  Oncol Lett       Date:  2012-10-19       Impact factor: 2.967

8.  N-Acetylgalactosaminyltransferase-14 as a potential biomarker for breast cancer by immunohistochemistry.

Authors:  Chen Wu; Xiaodan Guo; Weina Wang; Yun Wang; Yaojun Shan; Bo Zhang; Wenqian Song; Sisi Ma; Jianfeng Ge; Hao Deng; Mingsheng Zhu
Journal:  BMC Cancer       Date:  2010-04-01       Impact factor: 4.430

Review 9.  Recent insights into the biological roles of mucin-type O-glycosylation.

Authors:  E Tian; Kelly G Ten Hagen
Journal:  Glycoconj J       Date:  2008-08-10       Impact factor: 2.916

10.  The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation.

Authors:  Thomas A Gerken; Leslie Revoredo; Joseph J C Thome; Lawrence A Tabak; Malene Bech Vester-Christensen; Henrik Clausen; Gagandeep K Gahlay; Donald L Jarvis; Roy W Johnson; Heather A Moniz; Kelley Moremen
Journal:  J Biol Chem       Date:  2013-05-20       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.