Survival and prognostic indicators for dogs with intrahepatic portosystemic shunts: 32 cases (1990-2000).

OBJECTIVE: To determine prognostic indicators for short-term outcome and long-term survival for dogs with intrahepatic portosystemic shunts (IPSS). STUDY
DESIGN: Retrospective study. ANIMALS: Thirty-two dogs of various breeds.
METHODS: Clinical data extracted from medical records of dogs with IPSS were reviewed and included gender, age at surgery, weight, preoperative packed cell volume (PCV), total plasma protein concentration (TP), albumin (ALB), serum activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP), preprandial and postprandial bile acid concentrations (pre-BA, post-BA), blood urea nitrogen (BUN), glucose concentration, band neutrophils, per-rectal nuclear scintigraphy shunt fraction, whether an angiogram was performed, shunt location at surgery, whether a partial or complete attenuation of the shunt was performed, rectal temperature at the end of surgery, and duration of surgical procedure. Follow-up was determined from visits to the veterinary teaching hospital or by telephone communications with the owner or referring veterinarian.
RESULTS: Median survival time was 35.68 months, and 1- and 2-year probabilities of survival were 60% and 55%, respectively. Body weight, TP, ALB, and BUN were identified as prognostic indicators for short-term outcome. PCV and TP were identified as prognostic indicators for long-term survival.
CONCLUSIONS: PCV and TP were identified as prognostic indicators for long-term survival, whereas body weight, TP, ALB, and BUN were identified as indicators for short-term outcome in dogs with IPSS. Shunt location at surgery did not have any effect on short-term outcome and long-term survival. CLINICAL RELEVANCE: Total protein, ALB, BUN, and PCV can be used to determine prognosis of dogs with intrahepatic shunt. Copyright 2002 by The American College of Veterinary Surgeons