Literature DB >> 12415302

Lamins: building blocks or regulators of gene expression?

Christopher J Hutchison1.   

Abstract

Intermediate filament (IF) proteins are the building blocks of cytoskeletal filaments, the main function of which is to maintain cell shape and integrity. The lamins are thought to be the evolutionary progenitors of IF proteins and they have profound influences on both nuclear structure and function. These influences require the lamins to have dynamic properties and dual identities--as building blocks and transcriptional regulators. Which one of these identities underlies a myriad of genetic diseases is a topic of intense debate.

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Year:  2002        PMID： 12415302     DOI： 10.1038/nrm950

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  94 in total

1.  LINCing lamin B2 to neuronal migration: growing evidence for cell-specific roles of B-type lamins.

Authors:  Catherine Coffinier; Loren G Fong; Stephen G Young
Journal:  Nucleus       Date:  2010 Sep-Oct       Impact factor: 4.197

2.  Novel nuclear herniations induced by nuclear localization of a viral protein.

Authors:  Cristen C Hoyt; Ron J Bouchard; Kenneth L Tyler
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

3.  B-type lamins and their elusive roles in metazoan cell proliferation and senescence.

Authors:  Christopher J Hutchison
Journal:  EMBO J       Date:  2012-02-17       Impact factor: 11.598

4.  Reorganization of Nuclear Pore Complexes and the Lamina in Late-Stage Parvovirus Infection.

Authors:  Elina Mäntylä; Einari A Niskanen; Teemu O Ihalainen; Maija Vihinen-Ranta
Journal:  J Virol       Date:  2015-08-26       Impact factor: 5.103

5.  Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope.

Authors:  Thorsten Libotte; Hafida Zaim; Sabu Abraham; V C Padmakumar; Maria Schneider; Wenshu Lu; Martina Munck; Christopher Hutchison; Manfred Wehnert; Birthe Fahrenkrog; Ursula Sauder; Ueli Aebi; Angelika A Noegel; Iakowos Karakesisoglou
Journal:  Mol Biol Cell       Date:  2005-04-20       Impact factor: 4.138

6.  Lamin A N-terminal phosphorylation is associated with myoblast activation: impairment in Emery-Dreifuss muscular dystrophy.

Authors:  V Cenni; P Sabatelli; E Mattioli; S Marmiroli; C Capanni; A Ognibene; S Squarzoni; N M Maraldi; G Bonne; M Columbaro; L Merlini; G Lattanzi
Journal:  J Med Genet       Date:  2005-03       Impact factor: 6.318

Review 7.  Mendelian forms of structural cardiovascular disease.

Authors:  Calum A MacRae
Journal:  Curr Cardiol Rep       Date:  2013-10       Impact factor: 2.931

Review 8.  Posttranslational modifications of desmin and their implication in biological processes and pathologies.

Authors:  Daniel L Winter; Denise Paulin; Mathias Mericskay; Zhenlin Li
Journal:  Histochem Cell Biol       Date:  2013-10-04       Impact factor: 4.304

9.  Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.

Authors:  Meng Han; Miao Zhao; Chen Cheng; Yuan Huang; Shengna Han; Wenjuan Li; Xin Tu; Xuan Luo; Xiaoling Yu; Yinan Liu; Qiuyun Chen; Xiang Ren; Qing Kenneth Wang; Tie Ke
Journal:  Hum Mutat       Date:  2018-12-08       Impact factor: 4.878

10.  The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations.

Authors:  Vivian Chen; Malik Moncalvo; Dominic Tringali; Lidia Tagliafierro; Ahila Shriskanda; Ekaterina Ilich; Wendy Dong; Boris Kantor; Ornit Chiba-Falek
Journal:  Hum Mol Genet       Date:  2020-11-04       Impact factor: 6.150
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