Literature DB >> 12414923

Inhibition of polyomavirus ori-dependent DNA replication by mSin3B.

An-Yong Xie1, William R Folk.   

Abstract

When tethered in cis to DNA, the transcriptional corepressor mSin3B inhibits polyomavirus (Py) ori-dependent DNA replication in vivo. Histone deacetylases (HDACs) appear not to be involved, since tethering class I and class II HDACs in cis does not inhibit replication and treating the cells with trichostatin A does not specifically relieve inhibition by mSin3B. However, the mSin3B L59P mutation that impairs mSin3B interaction with N-CoR/SMRT abrogates inhibition of replication, suggesting the involvement of N-CoR/SMRT. Py large T antigen interacts with mSin3B, suggesting an HDAC-independent mechanism by which mSin3B inhibits DNA replication.

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Year:  2002        PMID： 12414923      PMCID： PMC136908          DOI： 10.1128/jvi.76.23.11809-11818.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  102 in total

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Authors:  S H Yang; E Vickers; A Brehm; T Kouzarides; A D Sharrocks
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

2.  DNA replication control through interaction of E2F-RB and the origin recognition complex.

Authors:  G Bosco; W Du; T L Orr-Weaver
Journal:  Nat Cell Biol       Date:  2001-03       Impact factor: 28.824

3.  The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation.

Authors:  J T Zilfou; W H Hoffman; M Sank; D L George; M Murphy
Journal:  Mol Cell Biol       Date:  2001-06       Impact factor: 4.272

Review 4.  The Rb/E2F pathway: expanding roles and emerging paradigms.

Authors:  J W Harbour; D C Dean
Journal:  Genes Dev       Date:  2000-10-01       Impact factor: 11.361

5.  The Sir1 protein's association with a silenced chromosome domain.

Authors:  K A Gardner; C A Fox
Journal:  Genes Dev       Date:  2001-01-15       Impact factor: 11.361

6.  Drosophila heterochromatin protein 1 (HP1)/origin recognition complex (ORC) protein is associated with HP1 and ORC and functions in heterochromatin-induced silencing.

Authors:  M M Shareef; C King; M Damaj; R Badagu; D W Huang; R Kellum
Journal:  Mol Biol Cell       Date:  2001-06       Impact factor: 4.138

7.  Identification of a nuclear domain with deacetylase activity.

Authors:  M Downes; P Ordentlich; H Y Kao; J G Alvarez; R M Evans
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-12       Impact factor: 11.205

8.  Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.

Authors:  J Li; J Wang; J Wang; Z Nawaz; J M Liu; J Qin; J Wong
Journal:  EMBO J       Date:  2000-08-15       Impact factor: 11.598

9.  The histone deacetylase-3 complex contains nuclear receptor corepressors.

Authors:  Y D Wen; V Perissi; L M Staszewski; W M Yang; A Krones; C K Glass; M G Rosenfeld; E Seto
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-20       Impact factor: 11.205

10.  RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.

Authors:  A Lai; B K Kennedy; D A Barbie; N R Bertos; X J Yang; M C Theberge; S C Tsai; E Seto; Y Zhang; A Kuzmichev; W S Lane; D Reinberg; E Harlow; P E Branton
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272
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  2 in total

1.  Histone deacetylase activity is necessary for chromosome condensation during meiotic maturation in Xenopus laevis.

Authors:  Laura Magnaghi-Jaulin; Christian Jaulin
Journal:  Chromosome Res       Date:  2006-04-20       Impact factor: 5.239

2.  Inhibition of transcription and DNA replication by the papillomavirus E8-E2C protein is mediated by interaction with corepressor molecules.

Authors:  Ingo Ammermann; Markus Bruckner; Frank Matthes; Thomas Iftner; Frank Stubenrauch
Journal:  J Virol       Date:  2008-03-19       Impact factor: 5.103
  2 in total

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