| Literature DB >> 12414354 |
Arianna Gonelli, Prisco Mirandola, Vittorio Grill, Paola Secchiero, Giorgio Zauli.
Abstract
In vitro infection of CD61+ megakaryocytic cells with human herpesvirus-7 (HHV-7) induced a drastic increase of apoptosis. Moreover, cells surviving HHV-7 cytotoxicity showed enhanced megakaryocytic maturation with respect to control cultures. These data suggest that HHV-7 reactivation in the bone marrow of HIV-1 infected individuals may contribute to impair megakaryocytopoiesis.Entities:
Mesh:
Year: 2002 PMID: 12414354
Source DB: PubMed Journal: Haematologica ISSN: 0390-6078 Impact factor: 9.941