Literature DB >> 12414094

Developmental changes in KCC1, KCC2, and NKCC1 mRNA expressions in the rat brain.

Cong Wang1, Chigusa Shimizu-Okabe, Kazuo Watanabe, Akihito Okabe, Hideo Matsuzaki, Tsuguhiro Ogawa, Norio Mori, Atsuo Fukuda, Kohji Sato.   

Abstract

We investigated the expressions of KCC1, KCC2 and NKCC1 mRNAs in the developing rat brain. The neuroepithelium showed abundant KCC1 and NKCC1 mRNA expressions, while KCC2 mRNA was not detected there. In contrast, KCC2 mRNA was preferentially expressed in postmitotic mature neurons. These results suggest that the appearance of KCC2 expression mainly depends on the maturation of individual neurons. Copyright 2002 Elsevier Science B.V.

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Year:  2002        PMID： 12414094     DOI： 10.1016/s0165-3806(02)00536-9

Source DB:  PubMed          Journal:  Brain Res Dev Brain Res        ISSN： 0165-3806


  61 in total

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