Literature DB >> 12413858

Synthesis and biological evaluation of new mannose 6-phosphate analogues.

Sébastien Vidal1, Marcel Garcia, Jean-Louis Montero, Alain Morère.   

Abstract

Three new analogues of mannose 6-phosphate (M6P)--a sulphate and two carboxylates--have been synthesized and their affinity toward the M6P/IGFII receptor evaluated by affinity column chromatography. These compounds display strong binding to the receptor and therefore are new M6P analogues which may find some dermatological applications, for example healing of post-surgical scars.

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Year:  2002        PMID: 12413858     DOI: 10.1016/s0968-0896(02)00264-x

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  4 in total

1.  Chemoenzymatic synthesis of ADP-d-glycero-β-d-manno-heptose and study of the substrate specificity of HldE.

Authors:  Tiehai Li; Liuqing Wen; Adriel Williams; Baolin Wu; Lei Li; Jingyao Qu; Jeffrey Meisner; Zhongying Xiao; Junqiang Fang; Peng George Wang
Journal:  Bioorg Med Chem       Date:  2013-12-19       Impact factor: 3.641

2.  A set of phosphatase-inert "molecular rulers" to probe for bivalent mannose 6-phosphate ligand-receptor interactions.

Authors:  Xiang Fei; Christopher M Connelly; Richard G MacDonald; David B Berkowitz
Journal:  Bioorg Med Chem Lett       Date:  2007-11-28       Impact factor: 2.823

Review 3.  Mannose 6-phosphate receptor targeting and its applications in human diseases.

Authors:  M Gary-Bobo; P Nirdé; A Jeanjean; A Morère; M Garcia
Journal:  Curr Med Chem       Date:  2007       Impact factor: 4.530

4.  Efficient Photodynamic Therapy of Prostate Cancer Cells through an Improved Targeting of the Cation-Independent Mannose 6-Phosphate Receptor.

Authors:  Elise Bouffard; Chiara Mauriello Jimenez; Khaled El Cheikh; Marie Maynadier; Ilaria Basile; Laurence Raehm; Christophe Nguyen; Magali Gary-Bobo; Marcel Garcia; Jean-Olivier Durand; Alain Morère
Journal:  Int J Mol Sci       Date:  2019-06-08       Impact factor: 5.923

  4 in total

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