Literature DB >> 12413484

Phosphatidylinositol 3,5-bisphosphate: metabolism and function.

Frank T Cooke1.   

Abstract

Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)) is the most recently discovered PtdInsP(2) isomer. It is likely that PtdIns(3,5)P(2) is ubiquitous to eukaryotes, and that it performs a number of important cellular functions, including vacuolar homeostasis, retrograde trafficking from the vacuole, and protein sorting at the multivesicular body. This review describes the metabolism of PtdIns(3,5)P(2) and discusses the potential functions for this lipid.

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Year:  2002        PMID: 12413484     DOI: 10.1016/s0003-9861(02)00487-3

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN: 0003-9861            Impact factor:   4.013


  7 in total

1.  Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors.

Authors:  Tor Erik Rusten; Lina M W Rodahl; Krupa Pattni; Camilla Englund; Christos Samakovlis; Stephen Dove; Andreas Brech; Harald Stenmark
Journal:  Mol Biol Cell       Date:  2006-07-12       Impact factor: 4.138

2.  Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella.

Authors:  Markus C Kerr; Jack T H Wang; Natalie A Castro; Nicholas A Hamilton; Liam Town; Darren L Brown; Frederic A Meunier; Nat F Brown; Jennifer L Stow; Rohan D Teasdale
Journal:  EMBO J       Date:  2010-03-18       Impact factor: 11.598

3.  Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae.

Authors:  Mehdi Mollapour; John P Phelan; Stefan H Millson; Peter W Piper; Frank T Cooke
Journal:  Biochem J       Date:  2006-04-01       Impact factor: 3.857

Review 4.  The role of phosphoinositides in synapse function.

Authors:  Yoshibumi Ueda
Journal:  Mol Neurobiol       Date:  2014-06-17       Impact factor: 5.590

5.  Biallelic Mutations of VAC14 in Pediatric-Onset Neurological Disease.

Authors:  Guy M Lenk; Krystyna Szymanska; Grazyna Debska-Vielhaber; Malgorzata Rydzanicz; Anna Walczak; Monika Bekiesinska-Figatowska; Stefan Vielhaber; Kerstin Hallmann; Piotr Stawinski; Sonja Buehring; David A Hsu; Wolfram S Kunz; Miriam H Meisler; Rafal Ploski
Journal:  Am J Hum Genet       Date:  2016-06-09       Impact factor: 11.025

6.  Genome-wide analysis of AP-3-dependent protein transport in yeast.

Authors:  Vikram C Anand; Lydia Daboussi; Todd C Lorenz; Gregory S Payne
Journal:  Mol Biol Cell       Date:  2008-12-30       Impact factor: 4.138

7.  Identification and structural characterization of FYVE domain-containing proteins of Arabidopsis thaliana.

Authors:  Ewa Wywial; Shaneen M Singh
Journal:  BMC Plant Biol       Date:  2010-08-02       Impact factor: 4.215

  7 in total

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