AIM: To assess the possible cerebral haemodynamic changes occurring in preterm infants after blood transfusions. METHODS: Preterm infants who had undergone blood transfusions were prospectively studied using both near infrared spectroscopy and cerebral Doppler ultrasonography. RESULTS: Fourteen infants (mean gestational age 29.6 wk, SD 2.6; mean birthweight 1,430g, SD 332) were studied at the mean age of 29 (SD 14) d. A significant increase in oxygenated haemoglobin (O2Hb), deoxygenated haemoglobin (HHb), mixed cerebral oxygen saturation (SmO2) and change in cerebral blood volume occurred after transfusion. Between ultrasound parameters, we found a decrease in diastolic velocity and an increase in resistance index. CONCLUSION: Blood transfusions improve cerebral oxygen supply and induce a decrease in cerebral blood volume, probably due to an increase in cerebral vessel resistance.
AIM: To assess the possible cerebral haemodynamic changes occurring in preterm infants after blood transfusions. METHODS: Preterm infants who had undergone blood transfusions were prospectively studied using both near infrared spectroscopy and cerebral Doppler ultrasonography. RESULTS: Fourteen infants (mean gestational age 29.6 wk, SD 2.6; mean birthweight 1,430g, SD 332) were studied at the mean age of 29 (SD 14) d. A significant increase in oxygenated haemoglobin (O2Hb), deoxygenated haemoglobin (HHb), mixed cerebral oxygen saturation (SmO2) and change in cerebral blood volume occurred after transfusion. Between ultrasound parameters, we found a decrease in diastolic velocity and an increase in resistance index. CONCLUSION: Blood transfusions improve cerebral oxygen supply and induce a decrease in cerebral blood volume, probably due to an increase in cerebral vessel resistance.
Authors: Ena Suppan; Gerhard Pichler; Corinna Binder-Heschl; Bernhard Schwaberger; Berndt Urlesberger Journal: Front Pediatr Date: 2022-06-13 Impact factor: 3.569
Authors: Graeme R Polglase; Suzanne L Miller; Samantha K Barton; Ana A Baburamani; Flora Y Wong; James D S Aridas; Andrew W Gill; Timothy J M Moss; Mary Tolcos; Martin Kluckow; Stuart B Hooper Journal: PLoS One Date: 2012-06-22 Impact factor: 3.240
Authors: Willemien S Kalteren; Elise A Verhagen; Jonathan P Mintzer; Arend F Bos; Elisabeth M W Kooi Journal: Front Pediatr Date: 2021-02-26 Impact factor: 3.418