Literature DB >> 12412476

Simultaneous humanization and affinity optimization of monoclonal antibodies.

Herren Wu1.   

Abstract

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Year:  2003        PMID： 12412476     DOI： 10.1385/1-59259-334-8:197

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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  3 in total

1.  Femtomolar Fab binding affinities to a protein target by alternative CDR residue co-optimization strategies without phage or cell surface display.

Authors:  Christian Votsmeier; Hanna Plittersdorf; Oliver Hesse; Andreas Scheidig; Michael Strerath; Uwe Gritzan; Klaus Pellengahr; Peter Scholz; Andrea Eicker; David Myszka; Wayne M Coco; Ulrich Haupts
Journal:  MAbs       Date:  2012-04-26       Impact factor: 5.857

2.  Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.

Authors:  Joey P Ting; Frances Tung; Stephen Antonysamy; Stephen Wasserman; Spencer B Jones; Feiyu F Zhang; Alfonso Espada; Howard Broughton; Michael J Chalmers; Michael E Woodman; Holly A Bina; Jeffrey A Dodge; Jordi Benach; Aiping Zhang; Christopher Groshong; Danalyn Manglicmot; Marijane Russell; Sepideh Afshar
Journal:  PLoS One       Date:  2018-01-12       Impact factor: 3.240

3.  Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design.

Authors:  Daniel A Cannon; Lu Shan; Qun Du; Lena Shirinian; Keith W Rickert; Kim L Rosenthal; Martin Korade; Lilian E van Vlerken-Ysla; Andrew Buchanan; Tristan J Vaughan; Melissa M Damschroder; Bojana Popovic
Journal:  PLoS Comput Biol       Date:  2019-05-01       Impact factor: 4.475
  3 in total

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