Renée D Goodwin1, Jack M Gorman. 1. Department of Epidemiology and Psychiatry, Columbia Unversity College of Physicians and Surgeons, New York, NY 10032, USA.
Abstract
OBJECTIVE: The authors sought to determine the association between treatment for generalized anxiety disorder and the risk of major depression among adults in the community. METHOD: Data were drawn from the National Comorbidity Survey (N=8,098), a representative sample of the United States population age 15-54. Cox proportional hazards were used to determine the association between specific forms of treatment for generalized anxiety disorder and the risk of major depression. RESULTS: Psychopharmacologic treatment of generalized anxiety disorder was associated with a significantly lower risk of major depression. There was no significant association between either having seen a mental health professional for generalized anxiety disorder or having been prescribed a medication for generalized anxiety disorder and the risk of depression. CONCLUSIONS: These results suggest an association between treatment for generalized anxiety disorder and lower risk of depression, which appears specific to pharmacologic treatment. Future research that leads to a more precise delineation of the underlying mechanism of the observed association is needed to identify and develop effective strategies to prevent onset of depression.
OBJECTIVE: The authors sought to determine the association between treatment for generalized anxiety disorder and the risk of major depression among adults in the community. METHOD: Data were drawn from the National Comorbidity Survey (N=8,098), a representative sample of the United States population age 15-54. Cox proportional hazards were used to determine the association between specific forms of treatment for generalized anxiety disorder and the risk of major depression. RESULTS: Psychopharmacologic treatment of generalized anxiety disorder was associated with a significantly lower risk of major depression. There was no significant association between either having seen a mental health professional for generalized anxiety disorder or having been prescribed a medication for generalized anxiety disorder and the risk of depression. CONCLUSIONS: These results suggest an association between treatment for generalized anxiety disorder and lower risk of depression, which appears specific to pharmacologic treatment. Future research that leads to a more precise delineation of the underlying mechanism of the observed association is needed to identify and develop effective strategies to prevent onset of depression.
Authors: R C Kessler; N A Sampson; P Berglund; M J Gruber; A Al-Hamzawi; L Andrade; B Bunting; K Demyttenaere; S Florescu; G de Girolamo; O Gureje; Y He; C Hu; Y Huang; E Karam; V Kovess-Masfety; S Lee; D Levinson; M E Medina Mora; J Moskalewicz; Y Nakamura; F Navarro-Mateu; M A Oakley Browne; M Piazza; J Posada-Villa; T Slade; M Ten Have; Y Torres; G Vilagut; M Xavier; Z Zarkov; V Shahly; M A Wilcox Journal: Epidemiol Psychiatr Sci Date: 2015-02-27 Impact factor: 6.892
Authors: Juan Angel Bellón; Berta Moreno-Küstner; Francisco Torres-González; Carmen Montón-Franco; María Josefa GildeGómez-Barragán; Marta Sánchez-Celaya; Miguel Angel Díaz-Barreiros; Catalina Vicens; Juan de Dios Luna; Jorge A Cervilla; Blanca Gutierrez; María Teresa Martínez-Cañavate; Bárbara Oliván-Blázquez; Ana Vázquez-Medrano; María Soledad Sánchez-Artiaga; Sebastia March; Emma Motrico; Victor Manuel Ruiz-García; Paulette Renée Brangier-Wainberg; María Del Mar Muñoz-García; Irwin Nazareth; Michael King Journal: BMC Public Health Date: 2008-07-25 Impact factor: 3.295