| Literature DB >> 12408896 |
Tomás Pérez-Ruiz1, C Martinez-Lozano, V Tomás, E Bravo, R Galera.
Abstract
A simple and sensitive capillary electrophoresis method using UV detection has been developed for the direct determination of ranitidine (RANT) and famotidine (FAMT) in serum, urine and pharmaceutical formulations. A buffer consisting of 60 mM phosphate buffer adjusted to pH 6.5 was found to provide a very efficient and stable electrophoretic system for the analysis of both drugs. The detection limits obtained were 0.088 microgram ml(-1) for RANT and 0.16 microgram ml(-1) for FAMT.Entities:
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Year: 2002 PMID： 12408896 DOI： 10.1016/s0731-7085(02)00444-2
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935