| Literature DB >> 12408860 |
Abby F Dernburg1, Gary H Karpen.
Abstract
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.Mesh:
Substances:
Year: 2002 PMID: 12408860 DOI: 10.1016/s0092-8674(02)01039-5
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582