Literature DB >> 12408857

Dueling activities of AIF in cell death versus survival: DNA binding and redox activity.

Stuart A Lipton1, Ella Bossy-Wetzel.   

Abstract

Apoptosis-inducing factor (AIF) was originally discovered as a mitochondrial protein that, like cytochrome c, is released into the cytoplasm during cell death. New evidence suggests, however, that a redox-active enzymatic region of AIF may be antiapoptotic while a DNA binding region is proapoptotic.

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Year:  2002        PMID: 12408857     DOI: 10.1016/s0092-8674(02)01046-2

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  47 in total

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Review 4.  Divide and die: cell cycle events as triggers of nerve cell death.

Authors:  Karl Herrup; Rachael Neve; Susan L Ackerman; Agata Copani
Journal:  J Neurosci       Date:  2004-10-20       Impact factor: 6.167

5.  Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

Authors:  Claire M Payne; Cheray Crowley-Skillicorn; Carol Bernstein; Hana Holubec; Harris Bernstein
Journal:  Clin Exp Gastroenterol       Date:  2011-05-03

Review 6.  Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage.

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Journal:  Heart Fail Rev       Date:  2008-06       Impact factor: 4.214

7.  The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells.

Authors:  Rui Huang; Xue-Qin Chen; Ying Huang; Ni Chen; Hao Zeng
Journal:  Asian J Androl       Date:  2010-05-17       Impact factor: 3.285

8.  The involvement of proliferation and apoptosis in the early human gonad development.

Authors:  T Vukusic Pusic; T Janjic; I Dujmovic; A Poljicanin; V Soljic; M Saraga-Babic; K Vukojevic
Journal:  J Mol Histol       Date:  2012-10-17       Impact factor: 2.611

9.  Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria.

Authors:  Shankar J Chinta; Anand Rane; Nagendra Yadava; Julie K Andersen; David G Nicholls; Brian M Polster
Journal:  Free Radic Biol Med       Date:  2009-04-01       Impact factor: 7.376

10.  Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathways.

Authors:  Amer Ali Abd El-Hafeez; Hazim O Khalifa; Rania Abdelrahman Elgawish; Samia A Shouman; Magdy Hussein Abd El-Twab; Seiji Kawamoto
Journal:  Cytotechnology       Date:  2018-01-25       Impact factor: 2.058

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