| Literature DB >> 12408839 |
Lisa McKerracher1, Matthew J Winton.
Abstract
Growth inhibition in the central nervous system (CNS) is a major barrier to axon regeneration. Recent findings indicate that three distinct myelin proteins, myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte-myelin glycoprotein (OMgp), inhibit axon growth by binding a common receptor, the Nogo66 receptor (NgR), and likely converge on a common signaling cascade.Entities:
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Year: 2002 PMID: 12408839 DOI: 10.1016/s0896-6273(02)01018-8
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173