| Literature DB >> 12408837 |
Abstract
Miller et al. (this issue of Neuron) report that deletion of the 3'UTR of alpha-CaMKII mRNA prevents dendritic delivery of the mRNA in transgenic mice and thus local synthesis of alpha-CaMKII protein in dendrites. 3'UTR mutant mice exhibit decreases in alpha-CaMKII protein in postsynaptic densities, and deficits in late phase LTP and in memory consolidation.Entities:
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Year: 2002 PMID: 12408837 DOI: 10.1016/s0896-6273(02)01006-1
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173