Literature DB >> 12408814

On the road to repair: PCNA encounters SUMO and ubiquitin modifications.

Michael J Matunis1.   

Abstract

The molecular events and targets regulated by the RAD6 pathway, which mediates postreplication DNA repair, have remained elusive. Now, ubiquitin and SUMO modification of proliferating cell nuclear antigen (PCNA) is shown to be induced by DNA damage and linked to components of the RAD6 pathway.

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Year:  2002        PMID： 12408814     DOI： 10.1016/s1097-2765(02)00653-6

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  18 in total

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2.  Nucleolin Binds to the Proliferating Cell Nuclear Antigen and Inhibits Nucleotide Excision Repair.

Authors:  Chonglin Yang; Myoung Sook Kim; Devulapalli Chakravarty; Fred E Indig; France Carrier
Journal:  Mol Cell Pharmacol       Date:  2009

3.  Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin.

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4.  Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

Authors:  Huajun Zhao; Yuan-Hung Lo; Li Ma; Susan E Waltz; Jerilyn K Gray; Mien-Chie Hung; Shao-Chun Wang
Journal:  Mol Cancer Ther       Date:  2011-01       Impact factor: 6.261

5.  Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development.

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Journal:  Mol Cell Biol       Date:  2005-06       Impact factor: 4.272

6.  The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer.

Authors:  H Zhao; M-S Chen; Y-H Lo; S E Waltz; J Wang; P-C Ho; J Vasiliauskas; R Plattner; Y-L Wang; S-C Wang
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7.  The Rad1-Rad10 complex promotes the production of gross chromosomal rearrangements from spontaneous DNA damage in Saccharomyces cerevisiae.

Authors:  Ji-Young Hwang; Stephanie Smith; Kyungjae Myung
Journal:  Genetics       Date:  2005-01-31       Impact factor: 4.562

8.  Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation.

Authors:  Keun Il Kim; Nadia V Giannakopoulos; Herbert W Virgin; Dong-Er Zhang
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272

9.  Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9.

Authors:  Amélie Fradet-Turcotte; Karine Brault; Steve Titolo; Peter M Howley; Jacques Archambault
Journal:  Virology       Date:  2009-12-20       Impact factor: 3.616

10.  X-ray survival characteristics and genetic analysis for nine Saccharomyces deletion mutants that show altered radiation sensitivity.

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Journal:  Genetics       Date:  2004-09-15       Impact factor: 4.562
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