Literature DB >> 12408577

Effects of single and combined exposures to benzo(a)pyrene and 3,3'4,4'5-pentachlorobiphenyl on EROD activity and development in Fundulus heteroclitus.

Deena M Wassenberg1, Erin E Swails, Richard T Di Giulio.   

Abstract

The goal of this study was to assess the interactive effects of a polynuclear aromatic hydrocarbon (PAH), benzo(a)pyrene (BaP), and a co-planar halogenated aromatic hydrocarbon (HAH), 3,3'4,4'5-pentachlorobiphenyl (PCB 126) on ethoxyresorufin-O-deethylase (EROD) activity and occurrence of deformities in Fundulus heteroclitus. While each compound administered alone elicited dose-dependent increases in EROD activity, the combined treatment of these two compounds generally did not elicit an additive EROD response. There was a significant correlation between deformity occurrence and EROD induction in embryos dosed with PCB alone but not for embryos dosed with BaP alone, or a combination of BaP and PCB 126.

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Year:  2002        PMID： 12408577     DOI： 10.1016/s0141-1136(02)00182-4

Source DB:  PubMed          Journal:  Mar Environ Res        ISSN： 0141-1136            Impact factor:   3.130


  6 in total

1.  Resistance to polycyclic aromatic hydrocarbon toxicity and associated bioenergetic consequences in a population of Fundulus heteroclitus.

Authors:  C D Lindberg; N Jayasundara; J S Kozal; T C Leuthner; R T Di Giulio
Journal:  Ecotoxicology       Date:  2017-02-17       Impact factor: 2.823

2.  An attempt to assess the relevance of flood events-biomarker response of rainbow trout exposed to resuspended natural sediments in an annular flume.

Authors:  Sebastian Hudjetz; Henning Herrmann; Catrina Cofalla; Markus Brinkmann; Ulrike Kammann; Andreas Schäffer; Holger Schüttrumpf; Henner Hollert
Journal:  Environ Sci Pollut Res Int       Date:  2013-12-15       Impact factor: 4.223

3.  Antioxidant responses in clam Venerupis philippinarum exposed to environmental pollutant hexabromocyclododecane.

Authors:  Hui Zhang; Luqing Pan; Yanxia Tao
Journal:  Environ Sci Pollut Res Int       Date:  2014-03-29       Impact factor: 4.223

4.  The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus).

Authors:  Dawoon Jung; Youngeun Cho; Joel N Meyer; Richard T Di Giulio
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2008-07-24       Impact factor: 3.228

5.  Fluoranthene, but not benzo[a]pyrene, interacts with hypoxia resulting in pericardial effusion and lordosis in developing zebrafish.

Authors:  Cole W Matson; Alicia R Timme-Laragy; Richard T Di Giulio
Journal:  Chemosphere       Date:  2008-10-05       Impact factor: 7.086

6.  AHR-related activities in a creosote-adapted population of adult atlantic killifish, Fundulus heteroclitus, two decades post-EPA superfund status at the Atlantic Wood Site, Portsmouth, VA USA.

Authors:  Josephine V Wojdylo; Wolfgang Vogelbein; Lisa J Bain; Charles D Rice
Journal:  Aquat Toxicol       Date:  2016-05-22       Impact factor: 4.964
  6 in total

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