| Literature DB >> 12408477 |
Steven M Crooks1, Andrei Pugachev, Christopher King, Lei Xing.
Abstract
Within the confines of least-squares operations, it is possible to quantify the effect of the addition of treatment fields or beamlets to a treatment plan. Using linear algebra and eigenvalue perturbation theory, the effect of the increase in number of treatments is shown to be equivalent to adding a perturbation operator. The effect of adding additional fields will be negligible if the perturbation operator is small. The correspondence of this approach to an earlier work in beam-orientation optimization is also demonstrated. Results are presented for prostate, spinal and head and neck cases, and the connection to beam-orientation optimization is examined.Mesh:
Year: 2002 PMID: 12408477 DOI: 10.1088/0031-9155/47/19/304
Source DB: PubMed Journal: Phys Med Biol ISSN: 0031-9155 Impact factor: 3.609