Literature DB >> 12408307

The medical-irradiation characteristics for neutron capture therapy at the Heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor.

Yoshinori Sakurai1, Tooru Kobayashi.   

Abstract

At the Heavy Water Neutron Irradiation Facility of the Kyoto University Research Reactor, the mix irradiation of thermal and epi-thermal neutrons, and the solo irradiation of epi-thermal neutrons are available additionally to the thermal neutron irradiation, and then the neutron capture therapy (NCT) at this facility became more flexible, after the update in 1996. The estimation of the depth dose distributions in NCT clinical irradiation, were performed for the standard irradiation modes of thermal, mixed and epi-thermal neutrons, from the both sides of experiment and calculation. On the assumption that the 10B concentration in tumor part was 40 ppm and the ratio of tumor to normal tissue was 3.5, the advantage depth were estimated to 5.4, 6.0, and 8.0, for the respective standard irradiation modes. It was confirmed that the various irradiation conditions can be selected according to the target-volume conditions, such as size, depth, etc. Besides, in the viewpoint of the radiation shielding for patient, it was confirmed that the whole-body exposure is effectively reduced by the new clinical collimators, compared with the old one.

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Year:  2002        PMID: 12408307     DOI: 10.1118/1.1509444

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  5 in total

1.  Cerebrospinal fluid dissemination of high-grade gliomas following boron neutron capture therapy occurs more frequently in the small cell subtype of IDH1R132H mutation-negative glioblastoma.

Authors:  Natsuko Kondo; Rolf F Barth; Shin-Ichi Miyatake; Shinji Kawabata; Minoru Suzuki; Koji Ono; Norman L Lehman
Journal:  J Neurooncol       Date:  2017-05-22       Impact factor: 4.130

2.  Determining a methodology of dosimetric quality assurance for commercially available accelerator-based boron neutron capture therapy system.

Authors:  Katsumi Hirose; Takahiro Kato; Takaomi Harada; Tomoaki Motoyanagi; Hiroki Tanaka; Akihiko Takeuchi; Ryohei Kato; Shinya Komori; Yuhei Yamazaki; Kazuhiro Arai; Noriyuki Kadoya; Mariko Sato; Yoshihiro Takai
Journal:  J Radiat Res       Date:  2022-07-19       Impact factor: 2.438

3.  Evaluation of radioactivity in the bodies of mice induced by neutron exposure from an epi-thermal neutron source of an accelerator-based boron neutron capture therapy system.

Authors:  Satoshi Nakamura; Shoji Imamichi; Kazuyoshi Masumoto; Masashi Ito; Akihisa Wakita; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Kazuma Kobayashi; Yoshihisa Abe; Hiroshi Igaki; Kazuyoshi Kurita; Teiji Nishio; Mitsuko Masutani; Jun Itami
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2017       Impact factor: 3.493

4.  Profile analysis of adverse events after boron neutron capture therapy for head and neck cancer: a sub-analysis of the JHN002 study.

Authors:  Katsumi Hirose; Mariko Sato; Takahiro Kato; Kanako Takayama; Motohisa Suzuki; Hisashi Yamaguchi; Ichiro Seto; Yasuhiro Kikuchi; Masao Murakami; Yoshihiro Takai
Journal:  J Radiat Res       Date:  2022-05-18       Impact factor: 2.438

5.  Induced radioactivity in the blood of cancer patients following Boron Neutron Capture Therapy.

Authors:  Keiko Fujiwara; Yuko Kinashi; Tomoyuki Takahashi; Hiroshi Yashima; Kouta Kurihara; Yoshinori Sakurai; Hiroki Tanaka; Koji Ono; Sentaro Takahashi
Journal:  J Radiat Res       Date:  2013-02-07       Impact factor: 2.724

  5 in total

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