Sero-epidemiology of tetanus antibody among the children in eastern Turkey.

The aim of the study was to determine immunity status of children to tetanus, and to assess the Expanded Programme on Immunization. A total of 840 children aged 0-71 months were randomly selected from three provinces in eastern Turkey by using cluster-sampling method. Blood samples were collected and enzyme linked immunoassay test was used to measure antibody levels. The percentage of the children who had antibody titres above the minimum protective level (0.01 IU/ml) was 80.0%. Only 10.6% of the children had antibody titres above the fully protective level (0.1 IU/ml). Antibody levels of children in rural areas were higher than those of children in urban areas. In children whose fathers were literate the levels were also higher than the others. Antibody level increased with the number of vaccine applications. Antibody levels were not consistent with immunization history obtained from parents. In this regard, our suggestion is that wound care management should not depend on immunization history obtained from parents if the vaccination programs are not effectively implemented. Most of the children in this study had antibody titres below the fully protective level.