| Literature DB >> 12406625 |
Judith A Egan1, Richard P Nugent, Crist N Filer.
Abstract
Tacrine and its analogues have shown promise as cognition enhancers and potential chemotherapeutic agents for Alzheimer's disease. [3H]tacrine was required to explore its mechanism of action via receptor binding assay and the radioligand was prepared by means of catalytic dehalogenation of several brominated precursors.Entities:
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Year: 2002 PMID： 12406625 DOI： 10.1016/s0969-8043(02)00168-9
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513