Literature DB >> 12405254

Dysphagia in Crohn's disease: a diagnostic challenge.

C Knoblauch1, P Netzer, U Scheurer, F Seibold.   

Abstract

Dysphagia is a rare manifestation in a patient with Crohn's disease. We report on the case of a patient with long-standing Crohn's disease who developed progressive dysphagia over 3 years. Endoscopy showed minimal distal oesophagitis with non-specific histological findings. Further investigation with cinematography, barium swallow and manometry established an achalasia-like motility disorder. Biopsies obtained from the oesophagus were non-specific. Balloon dilatation was performed. Initial success was followed by recurrent dysphagia. At repeat endoscopy, an oesophageal fistula was detected. An attempt at conservative medical management failed and oesophagectomy was successfully performed. Pathology results of the resected specimen confirmed the suspected diagnosis of oesophageal Crohn's disease. Even if achalasia is suspected in a Crohn's patient, it should be taken into consideration that the motility disorder could be the result of a transmural inflammation with or without fibrosis caused by Crohn's disease.

Entities:  

Mesh:

Year:  2002        PMID: 12405254     DOI: 10.1016/s1590-8658(02)80210-9

Source DB:  PubMed          Journal:  Dig Liver Dis        ISSN: 1590-8658            Impact factor:   4.088


  5 in total

1.  Double-Edged Sword: Esophageal and Colonic Crohn's Disease.

Authors:  Apurva Tandon; Charles Lombard; George Triadafilopoulos
Journal:  Dig Dis Sci       Date:  2015-08-30       Impact factor: 3.199

Review 2.  Gastrointestinal motility disorders in inflammatory bowel diseases.

Authors:  Gabrio Bassotti; Elisabetta Antonelli; Vincenzo Villanacci; Marianna Salemme; Manuela Coppola; Vito Annese
Journal:  World J Gastroenterol       Date:  2014-01-07       Impact factor: 5.742

3.  Crohn's disease of the esophagus.

Authors:  Kim L Isaacs
Journal:  Curr Treat Options Gastroenterol       Date:  2007-02

Review 4.  Abnormal gut motility in inflammatory bowel disease: an update.

Authors:  G Bassotti; E Antonelli; V Villanacci; R Nascimbeni; M P Dore; G M Pes; G Maconi
Journal:  Tech Coloproctol       Date:  2020-02-15       Impact factor: 3.781

5.  Tofacitinib for the treatment of tumor necrosis factor-α inhibitor refractory esophageal Crohn's disease: a case report.

Authors:  Sunina Nathoo; William A Hood; Sara Keihanian; Amy L Collinsworth; Sarah C Glover
Journal:  J Med Case Rep       Date:  2016-09-23
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.