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Literature DB >> 12404405

Recognition and Stabilization of Quadruplex DNA by a Potent New Telomerase Inhibitor: NMR Studies of the 2:1 Complex of a Pentacyclic Methylacridinium Cation with d(TTAGGGT)(4) We thank the EPSRC of the UK and AstraZeneca for financial support to E.G. M.F.G.S. and R.A.H. are supported by the Cancer Research Campaign of the UK.

Evripidis Gavathiotis¹, Robert A. Heald, Malcolm F. G. Stevens, Mark S. Searle.

Abstract

Year: 2001 PMID： 12404405 DOI： 10.1002/1521-3773(20011217)40:24<4749::aid-anie4749>3.0.co;2-i

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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16 in total

1. Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents.

Authors: Rupesh Nanjunda; Caterina Musetti; Arvind Kumar; Mohamed A Ismail; Abdelbasset A Farahat; Siming Wang; Claudia Sissi; Manlio Palumbo; David W Boykin; W David Wilson
Journal: Curr Pharm Des Date: 2012 Impact factor: 3.116

2. Molecular dynamics studies of the 3D structure and planar ligand binding of a quadruplex dimer.

Authors: Ming-Hui Li; Quan Luo; Xiang-Gui Xue; Ze-Sheng Li
Journal: J Mol Model Date: 2010-05-29 Impact factor: 1.810

3. Targeting human telomerase for cancer therapeutics.

Authors: Lionel Guittat; Patrizia Alberti; Dennis Gomez; Anne De Cian; Gaëlle Pennarun; Thibault Lemarteleur; Chafke Belmokhtar; Rajaa Paterski; Hamid Morjani; Chantal Trentesaux; Eliane Mandine; François Boussin; Patrick Mailliet; Laurent Lacroix; Jean-François Riou; Jean-Louis Mergny
Journal: Cytotechnology Date: 2004-06 Impact factor: 2.058

4. Submolecular dissection reveals strong and specific binding of polyamide-pyridostatin conjugates to human telomere interface.

Authors: Shankar Mandal; Yusuke Kawamoto; Zhizhou Yue; Kaori Hashiya; Yunxi Cui; Toshikazu Bando; Shankar Pandey; Mohammed Enamul Hoque; Mohammad Akter Hossain; Hiroshi Sugiyama; Hanbin Mao
Journal: Nucleic Acids Res Date: 2019-04-23 Impact factor: 16.971

5. Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA.

Authors: Andong Zhao; Suzanne E Howson; Chuanqi Zhao; Jinsong Ren; Peter Scott; Chunyu Wang; Xiaogang Qu
Journal: Nucleic Acids Res Date: 2017-05-19 Impact factor: 16.971

6. Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles.

Authors: Marco Frasconi; Zhichang Liu; Juying Lei; Yilei Wu; Elena Strekalova; Dmitry Malin; Michael W Ambrogio; Xinqi Chen; Youssry Y Botros; Vincent L Cryns; Jean-Pierre Sauvage; J Fraser Stoddart
Journal: J Am Chem Soc Date: 2013-07-25 Impact factor: 15.419

1. Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents.

2. Molecular dynamics studies of the 3D structure and planar ligand binding of a quadruplex dimer.

3. Targeting human telomerase for cancer therapeutics.

4. Submolecular dissection reveals strong and specific binding of polyamide-pyridostatin conjugates to human telomere interface.

5. Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA.

6. Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles.

Review 7. Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.

8. A platinum-quinacridine hybrid as a G-quadruplex ligand.

9. Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library.

10. Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes.