| Literature DB >> 12404013 |
Karen M Huang-Brown1, Faisal A Guhad.
Abstract
Oral gavage is an important procedure for drug discovery and efficacy studies using rodents. However, there are welfare issues related to the use of the method by inexperienced persons or for long-term studies. The authors describe an effective method of administering drugs to rats by mixing the drug with chocolate to provide a consistent and reliable method of oral drug delivery to large groups of rats for a long period of time.Entities:
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Year: 2002 PMID: 12404013 DOI: 10.1038/5000197
Source DB: PubMed Journal: Lab Anim (NY) ISSN: 0093-7355 Impact factor: 12.625