Literature DB >> 12403986

Neuroprotective and neurorestorative strategies for Parkinson's disease.

Ted M Dawson1, Valina L Dawson.   

Abstract

Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson's disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson's disease.

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Year:  2002        PMID： 12403986     DOI： 10.1038/nn941

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  38 in total

1.  Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

Authors:  Belén G Ramírez; Cristina Blázquez; Teresa Gómez del Pulgar; Manuel Guzmán; María L de Ceballos
Journal:  J Neurosci       Date:  2005-02-23       Impact factor: 6.167

2.  Low Levels of Prohibitin in Substantia Nigra Makes Dopaminergic Neurons Vulnerable in Parkinson's Disease.

Authors:  Debashis Dutta; Nilufar Ali; Emili Banerjee; Raghavendra Singh; Amit Naskar; Ramesh Kumar Paidi; Kochupurackal P Mohanakumar
Journal:  Mol Neurobiol       Date:  2017-01-06       Impact factor: 5.590

3.  Inhibition of hydrogen sulfide generation contributes to 1-methy-4-phenylpyridinium ion-induced neurotoxicity.

Authors:  Xiao-Qing Tang; Li-Li Fan; Yu-Juan Li; Xin-Tian Shen; Yuan-Yuan Zhuan; Jian-Qin He; Jin-Hua Xu; Bi Hu; Yuan-Jian Li
Journal:  Neurotox Res       Date:  2010-04-02       Impact factor: 3.911

4.  Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium ion.

Authors:  Xiao-Qing Tang; Heng-Rong Fang; Yu-Juan Li; Cheng-Fang Zhou; Yan-Kai Ren; Rong-Qian Chen; Chun-Yan Wang; Bi Hu
Journal:  Neurochem Res       Date:  2011-07-07       Impact factor: 3.996

Review 5.  Opportunities and challenges of pluripotent stem cell neurodegenerative disease models.

Authors:  Jackson Sandoe; Kevin Eggan
Journal:  Nat Neurosci       Date:  2013-06-25       Impact factor: 24.884

6.  Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans.

Authors:  Pengxiu Cao; Yiyuan Yuan; Elizabeth A Pehek; Alex R Moise; Ying Huang; Krzysztof Palczewski; Zhaoyang Feng
Journal:  PLoS One       Date:  2010-02-19       Impact factor: 3.240

7.  Intracellular methamphetamine prevents the dopamine-induced enhancement of neuronal firing.

Authors:  Kaustuv Saha; Danielle Sambo; Ben D Richardson; Landon M Lin; Brittany Butler; Laura Villarroel; Habibeh Khoshbouei
Journal:  J Biol Chem       Date:  2014-06-24       Impact factor: 5.157

Review 8.  Mitochondria in neurodegenerative disorders: regulation of the redox state and death signaling leading to neuronal death and survival.

Authors:  Makoto Naoi; Wakako Maruyama; Hong Yi; Keiko Inaba; Yukihiro Akao; Masayo Shamoto-Nagai
Journal:  J Neural Transm (Vienna)       Date:  2009-11       Impact factor: 3.575

Review 9.  Animal models of Parkinson's disease progression.

Authors:  Gloria E Meredith; Patricia K Sonsalla; Marie-Francoise Chesselet
Journal:  Acta Neuropathol       Date:  2008-02-14       Impact factor: 17.088

Review 10.  Proteomics in animal models of Alzheimer's and Parkinson's diseases.

Authors:  Renã A Sowell; Joshua B Owen; D Allan Butterfield
Journal:  Ageing Res Rev       Date:  2008-07-18       Impact factor: 10.895
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