Literature DB >> 12401490

Sensing nickel. NikRs with two pockets.

John D Helmann1.   

Abstract

NikR represses expression of a nickel transporter in response to elevated levels of Ni(II). Recent results suggest that repression is elicited by binding of nickel to a high-affinity site, but a low-affinity binding pocket may also play a role.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12401490     DOI: 10.1016/s1074-5521(02)00251-x

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  1 in total

1.  Structural basis of low-affinity nickel binding to the nickel-responsive transcription factor NikR from Escherichia coli.

Authors:  Christine M Phillips; Eric R Schreiter; Collin M Stultz; Catherine L Drennan
Journal:  Biochemistry       Date:  2010-09-14       Impact factor: 3.162

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.