| Literature DB >> 12400795 |
Michael K Pasque1, Tina Hanselman, Kim Shelton, Beth A Kehoe-Huck, Robyn Hedges, Stephen D Cassivi, Gregory A Ewald, Joseph G Rogers.
Abstract
Implantable left ventricular assist device (LVAD) drive-line exit site infection, an expected consequence of currently available device use, continues to be a significant limiting factor in long-term support. We theorize that the mechanism behind the establishment of the most chronic exit site infections involves a shearing torsion injury that disrupts the tissue adherence interface with the drive-line. The resulting neo-epithelialized drainage tract prevents permanent clearance of the infection with antibiotics alone. The proposed treatment strategy of established infections involves aggressive surgical excision of the involved exit site.Entities:
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Year: 2002 PMID: 12400795 DOI: 10.1016/s0003-4975(02)03752-9
Source DB: PubMed Journal: Ann Thorac Surg ISSN: 0003-4975 Impact factor: 4.330