Literature DB >> 12400383

[Influence of unilateral nephrectomy on aldosterone receptors in the remaining kidney in rats].

Iu A Akimov1, N S Kosithyn.   

Abstract

It was shown that the 30th day of compensatory kidney hypertrophy arising as a result of unilateral nephrectomy was accompanied by an increased binding of the mineralocorticoid hormone aldosterone by cytoplasmic receptors of the tubule cells of the remaining kidney. The transfer of aldosterone from cytoplasmic receptors to the nuclear receptors increased in the tubule cells of the hypertrophied kidney. This suggests that at the early stages hypertrophies are expressed as adaptive phenomena and phenomena related to intensified functioning of the organ fulfilling the double load.

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Year:  2002        PMID: 12400383

Source DB:  PubMed          Journal:  Izv Akad Nauk Ser Biol        ISSN: 1026-3470


  1 in total

Review 1.  RAAS escape: a real clinical entity that may be important in the progression of cardiovascular and renal disease.

Authors:  Jay Lakkis; Wei X Lu; Matthew R Weir
Journal:  Curr Hypertens Rep       Date:  2003-10       Impact factor: 5.369

  1 in total

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