| Literature DB >> 12399577 |
Abstract
Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.Mesh:
Substances:
Year: 2002 PMID: 12399577 DOI: 10.1126/science.1075510
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728